Structure-Based Rational Design of a Phosphotriesterase

In silico substrate docking of both stereoisomers of the pesticide chlorfenvinphos (CVP) in the phosphotriesterase from Agrobacterium radiobacter identified two residues (F131 and W132) that prevent productive substrate binding and cause stereospecificity. A variant (W131H/F132A) was designed that e...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Jackson, Colin J., Weir, Kahli, Herlt, Anthony, Khurana, Jeevan, Sutherland, Tara D., Horne, Irene, Easton, Christopher, Russell, Robyn J., Scott, Colin, Oakeshott, John G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Enzymology and Protein Engineering
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725513/
https://ncbi.nlm.nih.gov/pubmed/19502439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00629-09
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller