E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

Ubiquitin and ubiquitin-like proteins (UBLs) are directed to targets by cascades of E1, E2, and E3 enzymes. The largest ubiquitin E3 subclass consists of cullin-RING ligases (CRLs), which contain one each of several cullins (CUL1, 2, 3, 4, or 5) and RING proteins (RBX1 or 2). CRLs are activated by l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Huang, Danny T., Ayrault, Olivier, Hunt, Harold W., Taherbhoy, Asad M., Duda, David M., Scott, Daniel C., Borg, Laura A., Neale, Geoffrey, Murray, Peter J., Roussel, Martine F., Schulman, Brenda A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725360/
https://ncbi.nlm.nih.gov/pubmed/19250909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.01.011
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