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Prolonged exposure to LPS increases iron, heme, and p22(phox) levels and NADPH oxidase activity in human aortic endothelial cells: Inhibition by desferrioxamine

OBJECTIVE: Vascular oxidative stress and inflammation are contributing factors in atherosclerosis. We recently found that the iron chelator, desferrioxamine (DFO), suppresses NADPH oxidase-mediated oxidative stress and expression of cellular adhesion molecules in mice treated with lipopolysaccharide...

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Bibliografische gegevens
Hoofdauteurs: Li, Lixin, Frei, Balz
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724965/
https://ncbi.nlm.nih.gov/pubmed/19251588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.183210
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