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Prolonged exposure to LPS increases iron, heme, and p22(phox) levels and NADPH oxidase activity in human aortic endothelial cells: Inhibition by desferrioxamine
OBJECTIVE: Vascular oxidative stress and inflammation are contributing factors in atherosclerosis. We recently found that the iron chelator, desferrioxamine (DFO), suppresses NADPH oxidase-mediated oxidative stress and expression of cellular adhesion molecules in mice treated with lipopolysaccharide...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724965/ https://ncbi.nlm.nih.gov/pubmed/19251588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.183210 |
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