Clonal expansions and loss of receptor diversity in the naïve CD8 T cell repertoire of aged mice

Eitemau Tebyg

• Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus
  gan: Yager, Eric J., et al.
  Cyhoeddwyd: (2008)
• Impact of ageing on the response and repertoire of influenza virus-specific CD4 T cells
  gan: Lanzer, Kathleen G, et al.
  Cyhoeddwyd: (2014)
• T cell receptor repertoire in polymyositis: clonal expansion of autoaggressive CD8+ T cells
  Cyhoeddwyd: (1995)
• The narrowing of the CD8 T cell repertoire in old age
  gan: Blackman, Marcia A., et al.
  Cyhoeddwyd: (2011)
• Broadly reactive human CD4(+) T cells against Enterobacteriaceae are found in the naïve repertoire and are clonally expanded in the memory repertoire
  gan: Cassotta, Antonino, et al.
  Cyhoeddwyd: (2020)