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The narrowing of the CD8 T cell repertoire in old age
Immune function declines progressively with age, resulting in increased susceptibility of the elderly to infection and impaired responses to vaccines. A diverse repertoire of T cells is essential for a vigorous immune response, and an important manifestation of immune aging is the progressive loss o...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163762/ https://ncbi.nlm.nih.gov/pubmed/21652194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2011.05.005 |
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