Clinical and neuropathological features of the Arctic APP mutation causing early onset Alzheimer's disease

BACKGROUND: A majority of mutations within the amyloid β (Aβ) region of the amyloid precursor protein (APP) gene cause inherited forms of intracerebral haemorrhage. Most of these mutations may also cause cognitive impairment, but the Arctic APP mutation is the only known intra-Aβ mutation to date ca...

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Bibliografische gegevens
Hoofdauteurs: Basun, Hans, Bogdanovic, Nenad, Ingelsson, Martin, Almkvist, Ove, Näslund, Jan, Axelman, Karin, Bird, Thomas D., Nochlin, David, Schellenberg, Gerard D., Wahlund, Lars-Olof, Lannfelt, Lars
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723757/
https://ncbi.nlm.nih.gov/pubmed/18413473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneur.65.4.499
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