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Clinical and neuropathological features of the Arctic APP mutation causing early onset Alzheimer's disease

BACKGROUND: A majority of mutations within the amyloid β (Aβ) region of the amyloid precursor protein (APP) gene cause inherited forms of intracerebral haemorrhage. Most of these mutations may also cause cognitive impairment, but the Arctic APP mutation is the only known intra-Aβ mutation to date ca...

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Detalhes bibliográficos
Main Authors: Basun, Hans, Bogdanovic, Nenad, Ingelsson, Martin, Almkvist, Ove, Näslund, Jan, Axelman, Karin, Bird, Thomas D., Nochlin, David, Schellenberg, Gerard D., Wahlund, Lars-Olof, Lannfelt, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723757/
https://ncbi.nlm.nih.gov/pubmed/18413473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneur.65.4.499
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