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The Genetics and Neuropathology of Alzheimer’s Disease
Here we review the genetic causes and risks for Alzheimer’s disease (AD). Early work identified mutations in three genes that cause AD: APP, PSEN1 and PSEN2. Although mutations in these genes are rare causes of AD, their discovery had a major impact on our understanding of molecular mechanisms of AD...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708460/ https://ncbi.nlm.nih.gov/pubmed/22618995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-0996-2 |
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