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The Genetics and Neuropathology of Alzheimer’s Disease

Here we review the genetic causes and risks for Alzheimer’s disease (AD). Early work identified mutations in three genes that cause AD: APP, PSEN1 and PSEN2. Although mutations in these genes are rare causes of AD, their discovery had a major impact on our understanding of molecular mechanisms of AD...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Schellenberg, Gerard D., Montine, Thomas J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708460/
https://ncbi.nlm.nih.gov/pubmed/22618995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-012-0996-2
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