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Chemoselective Tryptophan Labeling with Rhodium Carbenoids at Mild pH

Significant improvements have been made to a previously reported tryptophan modification method using rhodium carbenoids in aqueous solution, allowing the reaction to proceed at pH 6–7. This technique is based on the discovery that tert-butylhydroxyl amine promotes indole modification with rhodium c...

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書目詳細資料
Main Authors: Antos, John M., McFarland, Jesse M., Iavarone, Anthony T., Francis, Matthew B.
格式: Artigo
語言:Inglês
出版: 2009
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722835/
https://ncbi.nlm.nih.gov/pubmed/19366262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja900094h
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