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Characterization of the Zebrafish atxn1/axh Gene Family

In mammals, ataxin-1 (ATXN1) is a member of a family of proteins in which each member contains an AXH domain. Expansion of the polyglutamine tract in ATXN1 causes the neurodegenerative disease spinocerebellar ataxia type 1 (SCA1) with prominent cerebellar pathology. Toward a further characterization...

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Autori principali: Carlson, Kerri M., Melcher, Laura, Lai, Shaojuan, Zoghbi, Huda Y., Clark, H. Brent, Orr, Harry T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722686/
https://ncbi.nlm.nih.gov/pubmed/19085187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01677060802399976
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