A carregar...
miR-19, miR-101, and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis
Spinocerebellar ataxia type 1 is caused by expansion of a translated CAG repeat in ataxin1. The level of the polyglutamine-expanded protein is one of the factors that contribute to disease severity. Here, we show that miR-19, miR-101, and miR-130 co-regulate ataxin1 levels and that their inhibition...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2574629/ https://ncbi.nlm.nih.gov/pubmed/18758459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2183 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|