Phosphorylation of ATXN1 at Ser776 in the cerebellum

Spinocerebellar ataxia type 1 (SCA1) is one of nine inherited neurodegenerative disorders caused by a mutant protein with an expanded polyglutamine tract. Phosphorylation of ataxin-1 (ATXN1) at serine 776 is implicated in SCA1 pathogenesis. Previous studies, utilizing transfected cell lines and a Dr...

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Main Authors: Jorgensen, Nathan D., Andresen, J. Michael, Lagalwar, Sara, Armstrong, Ben, Stevens, Sam, Byam, Courtney E., Duvick, Lisa A., Lai, Shaojuan, Jafar-Nejad, Paymaan, Zoghbi, Huda Y., Clark, H. Brent, Orr, Harry T.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754139/
https://ncbi.nlm.nih.gov/pubmed/19500214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06164.x
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