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Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes

Acetyl-CoA produced in mitochondria from carbohydrate or amino acid catabolism needs to reach the cytosol to initiate de novo synthesis of fatty acids. All eukaryotes analyzed so far use a citrate/malate shuttle to transfer acetyl group equivalents from the mitochondrial matrix to the cytosol. Here...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rivière, Loïc, Moreau, Patrick, Allmann, Stefan, Hahn, Matthias, Biran, Marc, Plazolles, Nicolas, Franconi, Jean-Michel, Boshart, Michael, Bringaud, Frédéric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722340/
https://ncbi.nlm.nih.gov/pubmed/19625628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903355106
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