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Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes
Acetyl-CoA produced in mitochondria from carbohydrate or amino acid catabolism needs to reach the cytosol to initiate de novo synthesis of fatty acids. All eukaryotes analyzed so far use a citrate/malate shuttle to transfer acetyl group equivalents from the mitochondrial matrix to the cytosol. Here...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2722340/ https://ncbi.nlm.nih.gov/pubmed/19625628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903355106 |
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