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Gluconeogenesis is essential for trypanosome development in the tsetse fly vector

In the glucose-free environment that is the midgut of the tsetse fly vector, the procyclic form of Trypanosoma brucei primarily uses proline to feed its central carbon and energy metabolism. In these conditions, the parasite needs to produce glucose 6-phosphate (G6P) through gluconeogenesis from met...

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הוצא לאור ב:	PLoS Pathog
Main Authors:	Wargnies, Marion, Bertiaux, Eloïse, Cahoreau, Edern, Ziebart, Nicole, Crouzols, Aline, Morand, Pauline, Biran, Marc, Allmann, Stefan, Hubert, Jane, Villafraz, Oriana, Millerioux, Yoann, Plazolles, Nicolas, Asencio, Corinne, Rivière, Loïc, Rotureau, Brice, Boshart, Michael, Portais, Jean-Charles, Bringaud, Frédéric
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science 2018
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6312356/ https://ncbi.nlm.nih.gov/pubmed/30557412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007502
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Gluconeogenesis is essential for trypanosome development in the tsetse fly vector

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