ATP Synthesis-coupled and -uncoupled Acetate Production from Acetyl-CoA by Mitochondrial Acetate:Succinate CoA-transferase and Acetyl-CoA Thioesterase in Trypanosoma

Insect stage trypanosomes use an “acetate shuttle” to transfer mitochondrial acetyl-CoA to the cytosol for the essential fatty acid biosynthesis. The mitochondrial acetate sources are acetate:succinate CoA-transferase (ASCT) and an unknown enzymatic activity. We have identified a gene encoding acety...

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Detalhes bibliográficos
Main Authors: Millerioux, Yoann, Morand, Pauline, Biran, Marc, Mazet, Muriel, Moreau, Patrick, Wargnies, Marion, Ebikeme, Charles, Deramchia, Kamel, Gales, Lara, Portais, Jean-Charles, Boshart, Michael, Franconi, Jean-Michel, Bringaud, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366814/
https://ncbi.nlm.nih.gov/pubmed/22474284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355404
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