Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently...

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Detalhes bibliográficos
Main Authors: Carlin, Aaron F., Chang, Yung-Chi, Areschoug, Thomas, Lindahl, Gunnar, Hurtado-Ziola, Nancy, King, Charles C., Varki, Ajit, Nizet, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722167/
https://ncbi.nlm.nih.gov/pubmed/19596804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090691
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