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Loss of Siglec expression on T lymphocytes during human evolution
We report here that human T cells give much stronger proliferative responses to specific activation via the T cell receptor (TCR) than those from chimpanzees, our closest evolutionary relatives. Nonspecific activation using phytohemagglutinin was robust in chimpanzee T cells, indicating that the muc...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472519/ https://ncbi.nlm.nih.gov/pubmed/16682635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510484103 |
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