Rapid evolution of binding specificities and expression patterns of inhibitory CD33-related Siglecs in primates

Siglecs are sialic acid-binding Ig-like lectins that recognize sialoglycans via amino-terminal V-set domains. CD33-related Siglecs (CD33rSiglecs) on innate immune cells recognize endogenous sialoglycans as “self-associated molecular patterns” (SAMPs), dampening immune responses via cytosolic immunor...

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Detalhes bibliográficos
Main Authors: Padler-Karavani, Vered, Hurtado-Ziola, Nancy, Chang, Yung-Chi, Sonnenburg, Justin L., Ronaghy, Arash, Yu, Hai, Verhagen, Andrea, Nizet, Victor, Chen, Xi, Varki, Nissi, Varki, Ajit, Angata, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929681/
https://ncbi.nlm.nih.gov/pubmed/24308974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-241497
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