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Evidence for a human-specific mechanism for diet and antibody-mediated inflammation in carcinoma progression

Patients with cancer have circulating heterophile antibodies that agglutinate animal red cells via recognition of the mammalian cell surface sialic acid N-glycolylneuraminic acid (Neu5Gc), which was long considered an oncofetal antigen in humans. However, humans are genetically deficient in Neu5Gc p...

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Detalhes bibliográficos
Main Authors: Hedlund, Maria, Padler-Karavani, Vered, Varki, Nissi M., Varki, Ajit
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596253/
https://ncbi.nlm.nih.gov/pubmed/19017806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803943105
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