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Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease

Human heterophile antibodies that agglutinate animal erythrocytes are known to detect the nonhuman sialic acid N-glycolylneuraminic acid (Neu5Gc). This monosaccharide cannot by itself fill the binding site (paratope) of an antibody and can also be modified and presented in various linkages, on diver...

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Hlavní autoři: Padler-Karavani, Vered, Yu, Hai, Cao, Hongzhi, Chokhawala, Harshal, Karp, Felix, Varki, Nissi, Chen, Xi, Varki, Ajit
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586336/
https://ncbi.nlm.nih.gov/pubmed/18669916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwn072
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