Evolution of human-chimpanzee differences in malaria susceptibility: Relationship to human genetic loss of N-glycolylneuraminic acid

Chimpanzees are the closest evolutionary cousins of humans, sharing >99% identity in most protein sequences. Plasmodium falciparum is the major worldwide cause of malaria mortality. Plasmodium reichenowi, a morphologically identical and genetically very similar parasite, infects chimpanzees but n...

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Bibliographic Details
Main Authors: Martin, Maria J., Rayner, Julian C., Gagneux, Pascal, Barnwell, John W., Varki, Ajit
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1200275/
https://ncbi.nlm.nih.gov/pubmed/16126901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503819102
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