Loss of Anti-Bax Function in Gerstmann-Sträussler-Scheinker Syndrome-Associated Prion Protein Mutants

Previously, we have shown the loss of anti-Bax function in Creutzfeldt Jakob disease (CJD)-associated prion protein (PrP) mutants that are unable to generate cytosolic PrP (CyPrP). To determine if the anti-Bax function of PrP modulates the manifestation of prion diseases, we further investigated the...

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Detalles Bibliográficos
Main Authors: Jodoin, Julie, Misiewicz, Micheal, Makhijani, Priya, Giannopoulos, Paresa N., Hammond, Jennifer, Goodyer, Cynthia G., LeBlanc, Andréa C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722024/
https://ncbi.nlm.nih.gov/pubmed/19680558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006647
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