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Prion Protein on Astrocytes or in Extracellular Fluid Impedes Neurodegeneration Induced by Truncated Prion Protein

Prion protein (PrP) is a host-encoded membrane-anchored glycoprotein which is required for susceptibility to prion disease. PrP may also be important for normal brain functions such as hippocampal spatial memory. Previously transgenic mice expressing amino terminally truncated mouse PrP (Δ32–134) sp...

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Bibliografiska uppgifter
Huvudupphovsmän: Race, Brent, Meade-White, Kimberly, Race, Richard, Baumann, Frank, Aguzzi, Adriano, Chesebro, Bruce
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721470/
https://ncbi.nlm.nih.gov/pubmed/19332059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.03.017
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