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Lower specific infectivity of protease-resistant prion protein generated in cell-free reactions
Prions are unconventional infectious agents that cause transmissible spongiform encephalopathy (TSE) diseases, or prion diseases. The biochemical nature of the prion infectious agent remains unclear. Previously, using a protein misfolding cyclic amplification (PMCA) reaction, infectivity and disease...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228482/ https://ncbi.nlm.nih.gov/pubmed/22065744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111255108 |
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