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The challenge of selecting protein kinase assays for lead discovery optimization

BACKGROUND: Protein kinases represent one of the most promising groups of drug targets owing to their involvement in such pathological conditions as cancer, inflammatory diseases, neural disorders, and metabolism problems. In the last few years, numerous pharmaceutical and biotech companies have est...

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Detalhes bibliográficos
Main Authors: Ma, Haiching, Deacon, Sean, Horiuchi, Kurumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721227/
https://ncbi.nlm.nih.gov/pubmed/19662101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.3.6.607
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