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The challenge of selecting protein kinase assays for lead discovery optimization

BACKGROUND: Protein kinases represent one of the most promising groups of drug targets owing to their involvement in such pathological conditions as cancer, inflammatory diseases, neural disorders, and metabolism problems. In the last few years, numerous pharmaceutical and biotech companies have est...

詳細記述

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書誌詳細
主要な著者: Ma, Haiching, Deacon, Sean, Horiuchi, Kurumi
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721227/
https://ncbi.nlm.nih.gov/pubmed/19662101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.3.6.607
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