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The challenge of selecting protein kinase assays for lead discovery optimization

BACKGROUND: Protein kinases represent one of the most promising groups of drug targets owing to their involvement in such pathological conditions as cancer, inflammatory diseases, neural disorders, and metabolism problems. In the last few years, numerous pharmaceutical and biotech companies have est...

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Bibliografski detalji
Glavni autori: Ma, Haiching, Deacon, Sean, Horiuchi, Kurumi
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721227/
https://ncbi.nlm.nih.gov/pubmed/19662101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17460441.3.6.607
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