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Akt promotes BMP2-mediated osteoblast differentiation and bone development
Signaling through the IGF-I receptor by locally synthesized IGF-I or IGF-II is crucial for normal skeletal development and for bone remodeling. Osteogenesis is primarily regulated by bone morphogenetic proteins (BMPs), which activate gene expression programs driven by bone-specific transcription fac...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720922/ https://ncbi.nlm.nih.gov/pubmed/19208758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.042770 |
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