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Selective Signaling by Akt2 Promotes Bone Morphogenetic Protein 2-Mediated Osteoblast Differentiation

Mesenchymal stem cells are essential for repair of bone and other supporting tissues. Bone morphogenetic proteins (BMPs) promote commitment of these progenitors toward an osteoblast fate via functional interactions with osteogenic transcription factors, including Dlx3, Dlx5, and Runx2, and also can...

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Detalhes bibliográficos
Main Authors: Mukherjee, Aditi, Wilson, Elizabeth M., Rotwein, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815574/
https://ncbi.nlm.nih.gov/pubmed/19995912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01401-09
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