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Selective Signaling by Akt2 Promotes Bone Morphogenetic Protein 2-Mediated Osteoblast Differentiation
Mesenchymal stem cells are essential for repair of bone and other supporting tissues. Bone morphogenetic proteins (BMPs) promote commitment of these progenitors toward an osteoblast fate via functional interactions with osteogenic transcription factors, including Dlx3, Dlx5, and Runx2, and also can...
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Autori principali: | , , |
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Natura: | Artigo |
Lingua: | Inglês |
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American Society for Microbiology (ASM)
2010
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815574/ https://ncbi.nlm.nih.gov/pubmed/19995912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01401-09 |
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