High glucose promotes mineralization via bone morphogenetic protein 4-Smad signals in early stage of osteoblast differentiation

Diabetes mellitus is associated with bone fragility. Although osteoblast maturation is disturbed in patients with diabetes mellitus, the involvement of high glucose (HG) in different stages of osteoblast maturation is unclear. We used MC3T3-E1 cells, a murine osteoblastic cell line. The cells were i...

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Detalhes bibliográficos
Publicado no:Diabetol Int
Main Authors: Takeno, Ayumu, Kanazawa, Ippei, Tanaka, Ken-ichiro, Notsu, Masakazu, Kanasaki, Keizo, Oono, Takamasa, Ogawa, Yoshihiro, Sugimoto, Toshitsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943678/
https://ncbi.nlm.nih.gov/pubmed/33786272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13340-020-00463-5
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