High glucose promotes mineralization via bone morphogenetic protein 4-Smad signals in early stage of osteoblast differentiation

Diabetes mellitus is associated with bone fragility. Although osteoblast maturation is disturbed in patients with diabetes mellitus, the involvement of high glucose (HG) in different stages of osteoblast maturation is unclear. We used MC3T3-E1 cells, a murine osteoblastic cell line. The cells were i...

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Dades bibliogràfiques
Publicat a:Diabetol Int
Autors principals: Takeno, Ayumu, Kanazawa, Ippei, Tanaka, Ken-ichiro, Notsu, Masakazu, Kanasaki, Keizo, Oono, Takamasa, Ogawa, Yoshihiro, Sugimoto, Toshitsugu
Format: Artigo
Idioma:Inglês
Publicat: Springer Singapore 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943678/
https://ncbi.nlm.nih.gov/pubmed/33786272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13340-020-00463-5
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