Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway

Phloretin has pleiotropic effects, including glucose transporter (GLUT) inhibition. We previously showed that phloretin promoted adipogenesis of bone marrow stromal cell (BMSC) line ST2 independently of GLUT1 inhibition. This study investigated the effect of phloretin on osteoblastogenesis of ST2 ce...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Takeno, Ayumu, Kanazawa, Ippei, Tanaka, Ken-ichiro, Notsu, Masakazu, Sugimoto, Toshitsugu
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566987/
https://ncbi.nlm.nih.gov/pubmed/31137461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102481
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