Phloretin Suppresses Bone Morphogenetic Protein-2-Induced Osteoblastogenesis and Mineralization via Inhibition of Phosphatidylinositol 3-kinases/Akt Pathway

Phloretin has pleiotropic effects, including glucose transporter (GLUT) inhibition. We previously showed that phloretin promoted adipogenesis of bone marrow stromal cell (BMSC) line ST2 independently of GLUT1 inhibition. This study investigated the effect of phloretin on osteoblastogenesis of ST2 ce...

Full description

Saved in:
Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Takeno, Ayumu, Kanazawa, Ippei, Tanaka, Ken-ichiro, Notsu, Masakazu, Sugimoto, Toshitsugu
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566987/
https://ncbi.nlm.nih.gov/pubmed/31137461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102481
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items