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Changes in autoreactive T cell avidity during type 1 diabetes development
The activation threshold for antigen-specific T cell responses is dependent on the avidity of the trimolecular interaction between TCR, antigen, and MHC. We compared CD4+ T cell avidities for the diabetes-associated autoantigen glutamic acid decarboxylase 555-567 (GAD 555) among serial samples from...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720757/ https://ncbi.nlm.nih.gov/pubmed/19482555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.04.013 |
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