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Investigating the Role of T-Cell Avidity and Killing Efficacy in Relation to Type 1 Diabetes Prediction

During the progression of the clinical onset of Type 1 Diabetes (T1D), high-risk individuals exhibit multiple islet autoantibodies and high-avidity T cells which progressively destroy beta cells causing overt T1D. In particular, novel autoantibodies, such as those against IA-2 epitopes (aa1-577), ha...

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Библиографические подробности
Главные авторы: Khadra, Anmar, Pietropaolo, Massimo, Nepom, Gerald T., Sherman, Arthur
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091860/
https://ncbi.nlm.nih.gov/pubmed/21573001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014796
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