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Predictive Models of Type 1 Diabetes Progression: Understanding T-Cell Cycles and Their Implications on Autoantibody Release

Defining the role of T-cell avidity and killing efficacy in forming immunological response(s), leading to relapse-remission and autoantibody release in autoimmune type 1 diabetes (T1D), remains incompletely understood. Using competition-based population models of T- and B-cells, we provide a predict...

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Detalhes bibliográficos
Main Authors: Jaberi-Douraki, Majid, Pietropaolo, Massimo, Khadra, Anmar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976292/
https://ncbi.nlm.nih.gov/pubmed/24705439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093326
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