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Changes in autoreactive T cell avidity during type 1 diabetes development

The activation threshold for antigen-specific T cell responses is dependent on the avidity of the trimolecular interaction between TCR, antigen, and MHC. We compared CD4+ T cell avidities for the diabetes-associated autoantigen glutamic acid decarboxylase 555-567 (GAD 555) among serial samples from...

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Bibliografische gegevens
Hoofdauteurs: Standifer, Nathan E., Burwell, Emily A., Gersuk, Vivian H., Greenbaum, Carla J., Nepom, Gerald T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720757/
https://ncbi.nlm.nih.gov/pubmed/19482555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.04.013
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