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Modelling the kinetics of hepatitis C virus RNA decline over 4 weeks of treatment with pegylated interferon α-2b

Viral kinetic models for hepatitis C virus (HCV) have generally assumed that the effectiveness of therapy in blocking virion production, ε, is constant. However, with pegylated interferon α-2b (PEG-IFN) given weekly, there are significant changes in drug concentration between doses that may lead to...

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Bibliographic Details
Main Authors: Shudo, E., Ribeiro, R. M., Perelson, A. S.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720526/
https://ncbi.nlm.nih.gov/pubmed/18266841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2893.2008.00977.x
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