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Modeling Hepatitis C Virus Kinetics under Therapy using Pharmacokinetic and Pharmacodynamic Information

BACKGROUND: Mathematical models have proven helpful in analyzing the virological response to antiviral therapy in hepatitis C virus (HCV) infected subjects. OBJECTIVE: To summarize the uses and limitations of different models for analyzing HCV kinetic data under pegylated interferon therapy. METHODS...

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Autores principales: Shudo, Emi, Ribeiro, Ruy M., Perelson, Alan S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872514/
https://ncbi.nlm.nih.gov/pubmed/19331594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425250902787616
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