Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene

OBJECTIVE: Recent studies have demonstrated that genetic polymorphisms near the IL28B gene are associated with the clinical outcome of pegylated interferon α (peg-IFN-α) plus ribavirin therapy for patients with chronic hepatitis C virus (HCV). However, it is unclear whether genetic variations near t...

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Detalhes bibliográficos
Main Authors: Watanabe, Tsunamasa, Sugauchi, Fuminaka, Tanaka, Yasuhito, Matsuura, Kentaro, Yatsuhashi, Hiroshi, Murakami, Shuko, Iijima, Sayuki, Iio, Etsuko, Sugiyama, Masaya, Shimada, Takashi, Kakuni, Masakazu, Kohara, Michinori, Mizokami, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2013
Assuntos:
Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756516/
https://ncbi.nlm.nih.gov/pubmed/23135762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-302553
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