Leishmania donovani lacking the Golgi GDP-Man transporter LPG2 exhibit attenuated virulence in mammalian hosts

Surface phosophoglycans such as lipophosphoglycan (LPG) or proteophosphoglycan (PPG) and glycosylinositol phospholipids (GIPLs) modulate essential interactions between Leishmania and mammalian macrophages. Phosphoglycan synthesis depends on the Golgi GDP-mannose transporter encoded by LPG2. LPG2-nul...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Gaur, Upasna, Showalter, Melissa, Hickerson, Suzanne, Dalvi, Rahul, Turco, Salvatore J., Wilson, Mary E., Beverley, Stephen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720449/
https://ncbi.nlm.nih.gov/pubmed/19328787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2009.03.014
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares