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Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein
Telomerase is an essential cellular ribonucleoprotein (RNP) that solves the end replication problem and maintains chromosome stability by adding telomeric DNA to the termini of linear chromosomes1–3. Genetic mutations that abrogate normal assembly of telomerase RNP cause human disease4. It is thus o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720403/ https://ncbi.nlm.nih.gov/pubmed/17322903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05600 |
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