A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression

Epithelial-to-mesenchymal transition (EMT) plays an important role during normal embryogenesis, and it has been implicated in cancer invasion and metastasis. Here, we report that Ladybird homeobox 1 (LBX1), a developmentally regulated homeobox gene, directs expression of the known EMT inducers ZEB1,...

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Autori principali: Yu, Min, Smolen, Gromoslaw A., Zhang, Jianmin, Wittner, Ben, Schott, Benjamin J., Brachtel, Elena, Ramaswamy, Sridhar, Maheswaran, Shyamala, Haber, Daniel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2009
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720264/
https://ncbi.nlm.nih.gov/pubmed/19651985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1809309
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