Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1

Epithelial-mesenchymal transition (EMT) is thought to contribute to cancer metastasis, but its underlying mechanisms are not well understood. To define early steps in this cellular transformation, we analyzed human mammary epithelial cells with tightly regulated expression of Snail-1, a master regul...

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Detalhes bibliográficos
Main Authors: Javaid, Sarah, Zhang, Jianmin, Anderssen, Endre, Black, Josh C., Wittner, Ben S., Tajima, Ken, Ting, David T., Smolen, Gromoslaw A., Zubrowski, Matthew, Desai, Rushil, Maheswaran, Shyamala, Ramaswamy, Sridhar, Whetstine, Johnathan R., Haber, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034764/
https://ncbi.nlm.nih.gov/pubmed/24360956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.034
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