Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis

BACKGROUND: Dasatinib is a small molecule kinase inhibitor that has recently been shown to inhibit Src family kinases (SFK) and also has activity against CaP. Of importance to metastatic CaP, which frequently metastasises to bone, SFK are also vital to the regulation of bone remodelling. We sought t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Koreckij, T, Nguyen, H, Brown, L G, Yu, E Y, Vessella, R L, Corey, E
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720213/
https://ncbi.nlm.nih.gov/pubmed/19603032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605178
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker