Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis

Emerging evidence indicates that tumor-associated proteolytic remodeling of bone matrix may underlie the capacity of tumor cells to colonize and survive in the bone microenvironment. Of particular importance, urokinase-type plasminogen activator (uPA) has been shown to correlate with human prostate...

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Autori principali: Cher, Michael L., Biliran, Hector R., Bhagat, Sunita, Meng, Yonghong, Che, Mingxin, Lockett, Jaron, Abrams, Judith, Fridman, Rafael, Zachareas, Michael, Sheng, Shijie
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC164676/
https://ncbi.nlm.nih.gov/pubmed/12788977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1331360100
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