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Hypoxia in Bone Metastasis and Osteolysis

Hypoxia is a common feature in tumors, driving pathways that promote epithelial-to-mesenchymal transition, invasion, and metastasis. Clinically, high levels of hypoxia-inducible factor (HIF) expression and stabilization at the primary site in many cancer types is associated with poor patient outcome...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Todd, Vera M., Johnson, Rachelle W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429356/
https://ncbi.nlm.nih.gov/pubmed/32561416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.06.004
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