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Matrix Metalloproteinase Activity and Osteoclasts in Experimental Prostate Cancer Bone Metastasis Tissue

Previously, we and others showed that broad spectrum pharmaceutical inhibition of matrix metalloproteinase (MMP) activity reduces intraosseous tumor burden and bone degradation in animal models of bone metastasis. Herein, we used specific assays to measure net enzymatic activities of individual MMPs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dong, Zhong, Bonfil, R. Daniel, Chinni, Sreenivasa, Deng, Xiyun, Filho, J. Carlos Trindade, Bernardo, Margarida, Vaishampayan, Ulka, Che, Mingxin, Sloane, Bonnie F., Sheng, Shijie, Fridman, Rafael, Cher, Michael L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602391/
https://ncbi.nlm.nih.gov/pubmed/15793297
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