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Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis
BACKGROUND: Dasatinib is a small molecule kinase inhibitor that has recently been shown to inhibit Src family kinases (SFK) and also has activity against CaP. Of importance to metastatic CaP, which frequently metastasises to bone, SFK are also vital to the regulation of bone remodelling. We sought t...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2720213/ https://ncbi.nlm.nih.gov/pubmed/19603032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605178 |
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