Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia

Biliary atresia is a neonatal obstructive cholangiopathy that progresses to end-stage liver disease. Although the etiology is unknown, a neonatal adaptive immune signature has been mechanistically linked to obstruction of the extrahepatic bile ducts. Here, we investigated the role of the innate immu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shivakumar, Pranavkumar, Sabla, Gregg E., Whitington, Peter, Chougnet, Claire A., Bezerra, Jorge A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2009
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719928/
https://ncbi.nlm.nih.gov/pubmed/19662681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38879
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